Here is an excerpt from the interview:
Filmmaker: How did you attack that problem of taking a very complicated ensemble story and making it something an audience could easily grasp?
John: One thing I realized early on was that I had a bunch of white guys pretty much the same age with short haircuts wearing uniforms in the days before they had numbers on them. So I introduced each character three times in the opening twenty minutes or so. This is all done through action – either on the field, in the locker room or in the first stirrings of the conspiracy… I did choose three of the characters – Eddie Cicotte, Joe Jackson and Buck Weaver – to be more emotionally sympathetic, and they are the guys whose wives we meet. You always want to give the audience a way in to a movie, and when it has a complex plot it’s good to have a couple people to pick from to guide them along.